QA-17Updated 2026-05-19
What is PT-141 (Bremelanotide)?
PT-141 (Bremelanotide) is a synthetic analog of α-MSH that acts as a melanocortin-receptor agonist (MC3R/MC4R). It is studied in preclinical models for central-nervous-system sexual-behavior pathways and related neuroendocrine signaling.
PT-141 (Bremelanotide) is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH). It acts as a melanocortin-receptor agonist, with primary activity at the MC3R and MC4R receptors.
Research focus:
- Central sexual-behavior pathways — PT-141 acts in the central nervous system rather than peripherally on vascular tissue, distinguishing it mechanistically from PDE5-inhibitor small molecules.
- Neuroendocrine signaling mediated by the melanocortin receptor family.
- Behavioral pharmacology in preclinical models.
PT-141 is supplied for in-vitro and preclinical laboratory investigation only. See the Hormonal pathway for related neuroendocrine research peptides.
// Related research pathways