QA-10Updated 2026-05-19
What does GHK-Cu research show?
GHK-Cu is a copper-binding tripeptide (glycyl-histidyl-lysine bound to Cu²⁺) studied for its role in skin remodeling, collagen and elastin synthesis, antioxidant signaling, and wound-repair pathways in preclinical models.
GHK-Cu — glycyl-L-histidyl-L-lysine bound to a copper(II) ion — is one of the most-studied copper-binding peptides. It occurs naturally in human plasma and saliva, with concentrations that decline with age.
Research has investigated GHK-Cu for:
- Skin remodeling and collagen synthesis — fibroblast stimulation, glycosaminoglycan production.
- Antioxidant and anti-inflammatory signaling — modulation of TNF-α and other cytokines.
- Wound and tissue repair — effects on angiogenesis and macrophage activity.
- Hair follicle research — studied in preclinical follicle-stimulation models.
GHK-Cu is widely used in cosmetic research and topical-formulation studies. As supplied by ADAM Molecular Research, GHK-Cu is for in-vitro and preclinical laboratory investigation only.
Explore the broader Healing pathway for related compounds.
// Related research pathways